Increased expression of androgen receptor (AR) in prostate cancer (PC) is associated with transition to androgen independence.Because the progression of PC to advanced stages is often associated with the loss of p53 function, doorking video intercom we tested whether the p53 could regulate the expression of AR gene.Here we report that p53 negativel
Feasibility and Safety of Perioperative Chemotherapy With Fluorouracil Plus Leucovorin, Oxaliplatin, and Docetaxel for Locally Advanced Gastric Cancer Patients in China
BackgroundNeoadjuvant fluorouracil plus leucovorin, oxaliplatin, and docetaxel (FLOT) has shown significant benefits for gastric cancer patients.However, it has not been well accepted in Asian countries.We conducted a prospective study on the safety and feasibility of the FLOT regimen in Chinese patients.MethodsPatients with adenocarcinoma of the s